Subclinical atherosclerosis is associated with risk of CHD

Subclinical atherosclerosis is associated with risk of CHDSubclinical atherosclerosis, as measured by the indicator "intima media of the carotid arteries, is associated with premature development of coronary heart disease in parents. "Premature CHD family history is an independent risk factor for cardiovascular events, reminiscent of Dr. Christopher J. O'donnell and his colleagues who conducted the famous Framingham study. People with family anamnesis it is necessary carefully to examine, in a timely manner starting preventive measures. The researchers analyzed data 1662 participants Terminalskega studies, in which both parents were part of the original cohort. All patients underwent ULTRASOUND examination of the carotid arteries. The presence of the parents of premature CHD (60 years) was associated with large values of "intima-media of the internal carotid artery, even after adjusting for other factors of cardiovascular risk. Especially pronounced this tendency was for men. Moreover, the premature development of coronary heart disease in both parents or only one, as the development of its father or mother, to increase "intima-media" for the internal carotid artery had no effect. The same indicator for the common carotid artery, on the contrary, with the early development of coronary heart disease in parents was not associated. "Perhaps, this relationship is due to genetic reasons for the development of subclinical atherosclerosis, rather than the usual factors of cardiovascular risk," suggests Dr. O'donnell. "Now we have to determine the mechanisms of this relationship. Our goal is to develop new, effective strategies for early diagnosis and prevention of heart disease and stroke at a relatively young age.".



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